A Jack3d Cardiovascular System and Liver (2024)

FAQs

What effects does DMAA have on the heart? ›

DMAA, especially in combination with other stimulant ingredients such as caffeine, can be a health risk to consumers. Taking DMAA can raise blood pressure and lead to cardiovascular problems ranging from shortness of breath and tightening in the chest to heart attack.

Liver cirrhosis is associated with a wide range of cardiovascular abnormalities including hyperdynamic circulation, cirrhotic cardiomyopathy, and pulmonary vascular abnormalities. The pathogenic mechanisms of these cardiovascular changes are multifactorial and include neurohumoral and vascular dysregulations.

Jack3d (pronounced 'jacked') is a caffeinated pre-workout supplement that was banned in the U.S. in 2013 because of the illegal substance, dimethylamylamine (DMAA), though its updated formula sits on store shelves to this day.

At VitaminShoppe.com, where Jack3d is also sold, a reviewer boasts, “My muscles have gained mass like never before.” Yet, last April, federal health regulators issued a warning that the stimulant — called dimethylamylamine, or DMAA — frequently raises blood pressure and heart rate, and could lead to heart attacks.

There have been several reports of dangerous side effects including stroke, a condition called lactic acidosis, heart attack, liver injury, and death in people who have taken 1,3-DMAA.

Multiple products included in pre-workout supplements could predispose to cardiac ischemia. Most of these supplements have a high content of caffeine, nitric oxide, natural stimulants, or off-label products, which have represented numerous complications, including death.

The heart as a cause of liver disease. Heart failure often provokes liver damage, as it could be expected. In fact, the liver receives up to 25% of cardiac output, and is therefore highly sensitive to reduction in blood flow.

passing black, tarry poo and vomiting blood as a result of internal bleeding. a tendency to bleed and bruise more easily, such as frequent nosebleeds and bleeding gums. increased sensitivity to alcohol and drugs because the liver cannot process them.

"This has important public health and regulatory implications." E-cigarettes contain nicotine, which Dr. Friedman and other researchers have reported is associated with non-alcohol fatty liver diseases. However, the long-term effects of e-cigarettes on liver disease, diabetes, heart disease or stroke are unknown.

The Defense Department removed products containing DMAA, including Jack3d, from base stores and on-base GNCs in 2013 after the supplements were implicated in the deaths of at least two soldiers who suffered heart attacks during physical training.

How bad was Jack3d? ›

The FDA has received 86 adverse event reports believed to be linked to DMAA. Serious side effects reported to the FDA include depression, anxiety, vomiting, loss of consciousness, chest pain, and even death.

Manufactured in a cGMP-Certified Facility: All Jacked Factory products are manufactured under stringent quality control standards to ensure proper purity and potency. OUR formulas are completely free of harsh chemicals, fillers, and artificial food dyes.

Creatine is possibly safe when taken long-term. Doses up to 10 grams daily for up to 5 years have been safely used. Side effects might include dehydration, upset stomach, and muscle cramps.

NEUROFACTOR – Jack3d now contains Nootropics, directly stimulants Adrenaline and Dopamine. In elevated amounts these trigger enhanced cognitive function, focus, energy, motivation and fat burning.

how long after your last meal did you take it? you need at least 1.5-2hrs after your pre workout meal just to feel anything from jack3d, in my experience. alot of people say the same if you google it. It has 1 3 dimethylamylamine in it which certainly has an effect.

Surgery: DMHA might have stimulant effects. This might interfere with surgery by increasing heart rate and blood pressure. Stop taking DMHA at least 2 weeks before a scheduled surgery. Irregular heartbeat (heart arrhythmia): DMHA might have stimulant effects and cause a rapid heartbeat.

The inhibition by DMAA of the conversion of testosterone to 5 alpha-dihydrotestosterone by rat prostate 5 alpha-reductase is competitive with testosterone, the apparent Ki being 5 nM, and uncompetitive with NADPH, DMAA inhibited both membrane-bound and solubilized 5 alpha-reductase.

DMAA is a sympathomimetic and potent pressor agent. This report describes 3 cases of cerebral hemorrhage in adults after the use of DMAA.

The results from the Saudan laboratory found that 1,3-DMAA could be detected in urine samples up to 105 hours after administration of a 40 mg dose.