Pet1/FEV
ETS domain transcription factor, Pet-1, that is expressed in a small number of tissues, including the brain. Pet-1 is an early and precise marker of central serotonin neurons.
Cat. No | Product Name | Reactivity | Application |
DPABH-13854 | Anti-FEV (aa 149-198) polyclonal antibody | H | WB |
DPAB-DC2357 | Anti-FEV (aa 31-130) polyclonal antibody | H | WB,ELISA |
TPH1
Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase. Tryptophan hydroxylases catalyze the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5-HTP), which is subsequently decarboxylated to form the neurotransmitter serotonin (5-hydroxytryptamine or 5-HT). It is important for synthesizing indoleamine neurotransmitters and related compounds in the body and brain, including serotonin, melatonin, tryptamine, N-methyltryptamine, and N, N-dimethyltryptamine.
Cat. No | Product Name | Reactivity | Application |
DCABH-9108 | Anti-TPH1 monoclonal antibody, clone TD64-18 | H, M, R | WB, ICC/IF, IHC, IP, FC |
DPABH-01566 | Anti-Human TPH1 polyclonal antibody | H, M | WB, ELISA |
TPH2
Tryptophan hydroxylase 2 (TPH2) is an isozyme of tryptophan hydroxylase which is primarily expressed in the serotonergic neurons of the brain, with the highest expression in the raphe nucleus of the midbrain.
Cat. No | Product Name | Reactivity | Application |
DPABH-27086 | Anti-Human TPH2 polyclonal antibody | H, R | WB, ELISA |
CABT-L1643 | Anti-Human TPH2 monoclonal antibody, clone 0I2M7 | H, M, R | WB, ICC/IF |
DPABH-14559 | Anti-TPH2 (aa 16-29) polyclonal antibody | H, M, R | WB |
Serotonin Transporter/SLC6A4/5-HTTLPR
Serotonin Transporter (SERT) is a member of the Neurotransmitter-Sodium Symporter (NSS) family and is closely related to transporters for norepinephrine and dopamine, NET, and DAT, respectively. The function of SERT is to take up serotonin (5-HT) released by the activity of serotonergic neurons. It is located presynaptically on serotonergic axon terminals and are believed to serve as an index of serotonergic innervation.
Cat. No | Product Name | Reactivity | Application |
DPAB-DC2896 | Anti-SLC6A4 (aa 181-252) polyclonal antibody | H | WB, ELISA |
DCABH-7012 | Anti-Human SLC6A4 monoclonal antibody, clone 27I3M8 | H, M, R | WB, ICC/IF |