Serotonergic Neuron Markers Antibodies - Creative Diagnostics (2024)

Pet1/FEV

ETS domain transcription factor, Pet-1, that is expressed in a small number of tissues, including the brain. Pet-1 is an early and precise marker of central serotonin neurons.

Cat. No Product Name Reactivity Application
DPABH-13854Anti-FEV (aa 149-198) polyclonal antibodyHWB
DPAB-DC2357Anti-FEV (aa 31-130) polyclonal antibodyHWB,ELISA

See all Pet1/FEV antibodies

TPH1

Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase. Tryptophan hydroxylases catalyze the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5-HTP), which is subsequently decarboxylated to form the neurotransmitter serotonin (5-hydroxytryptamine or 5-HT). It is important for synthesizing indoleamine neurotransmitters and related compounds in the body and brain, including serotonin, melatonin, tryptamine, N-methyltryptamine, and N, N-dimethyltryptamine.

Cat. No Product Name Reactivity Application
DCABH-9108Anti-TPH1 monoclonal antibody, clone TD64-18H, M, RWB, ICC/IF, IHC, IP, FC
DPABH-01566Anti-Human TPH1 polyclonal antibodyH, MWB, ELISA

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TPH2

Tryptophan hydroxylase 2 (TPH2) is an isozyme of tryptophan hydroxylase which is primarily expressed in the serotonergic neurons of the brain, with the highest expression in the raphe nucleus of the midbrain.

Cat. No Product Name Reactivity Application
DPABH-27086Anti-Human TPH2 polyclonal antibodyH, RWB, ELISA
CABT-L1643Anti-Human TPH2 monoclonal antibody, clone 0I2M7H, M, RWB, ICC/IF
DPABH-14559Anti-TPH2 (aa 16-29) polyclonal antibodyH, M, RWB

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Serotonin Transporter/SLC6A4/5-HTTLPR

Serotonin Transporter (SERT) is a member of the Neurotransmitter-Sodium Symporter (NSS) family and is closely related to transporters for norepinephrine and dopamine, NET, and DAT, respectively. The function of SERT is to take up serotonin (5-HT) released by the activity of serotonergic neurons. It is located presynaptically on serotonergic axon terminals and are believed to serve as an index of serotonergic innervation.

Cat. No Product Name Reactivity Application
DPAB-DC2896Anti-SLC6A4 (aa 181-252) polyclonal antibodyHWB, ELISA
DCABH-7012Anti-Human SLC6A4 monoclonal antibody, clone 27I3M8H, M, RWB, ICC/IF

See all Serotonin Transporter/SLC6A4/5-HTTLPR antibodies

Serotonergic Neuron Markers Antibodies - Creative Diagnostics (2024)
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